路透社健康
2006年9月19日，星期二
华盛顿（路透社）――美国研究人员周二报道，引发宫颈癌的同一生殖疣病毒亦可减少女性在生育诊所（辅助生育诊所）受孕的机会。
研究人员发现，与57％未感染女性相比，感染人类乳突状瘤病毒（HPV）的女性中仅有23％在接受体外受精（IVF）治疗期间成功受孕。
“性传播疾病是不育的一个主要原因。然而，HPV感染和不育间的可能联系还未经系统研究。”研究人员在其报告中写道，此报告已发表于《生育和不育》杂志。
“遗憾的是，这种病毒在育龄人群中非常普遍。HPV检测可能成为IVF患者筛选试验的新增有用项目，这也可能有助于医师们向患者提出建议，”美国生殖医学学会主席Joseph Sanfilippo博士在一次陈述中说道。该学会出版这本杂志（《生育和不育》）。
研究人员没有对一般生育与HPV间的联系进行研究。
纽约医院•康奈尔大学医疗中心的Steven Spandorfer博士与其同事，对106位准备做IVF的患者进行了研究，这些患者均接受HPV、HIV、衣原体及淋病检测。
除了17位女性被检出HPV外，其他受试者均未感染。感染女性可能受孕的机会不及从未感染或已将病毒从体内成功清除的女性的一半。
据美国疾病控制与防治中心（CDC）称，生殖道HPV感染非常普遍。
CDC称，目前单在美国就约有2千万人感染了HPV。至少有50％性活跃的男女在其生命中的某一时刻会感染生殖道HPV――每年有超过六百二十万美国人感染。
HPV可引起宫颈癌，每年全球约有30万女性死于此病，其中就包括4000位美国人。
默克制药公司今年获得一项叫Gardasil的疫苗专利，该疫苗可预防HPV最危险的病毒株感染。疫苗专家建议大部分年轻女性性活跃前能接受此疫苗。
Wart virus reduces test-tube baby success
Reuters Health
Tuesday, September 19, 2006
WASHINGTON (Reuters) - The same genital wart virus that causes cervical cancer may also reduce a woman's chances of becoming pregnant at a fertility clinic, U.S. researchers reported on Tuesday.
Only 23 percent of women infected with human papillomavirus, or HPV, became pregnant during in-vitro fertility or IVF treatments, compared to 57 percent of uninfected women, the researchers found.
"Sexually transmitted diseases are a major cause of infertility. However, possible links between HPV infection and infertility have not been systematically investigated," the researchers wrote in their report, published in the journal Fertility and Sterility.
"Unfortunately, the virus is very common among people of reproductive age. Testing for HPV might become a useful addition to the screening tests done for IVF patients and could help physicians to advise them," Dr. Joseph Sanfilippo, president of the American Society for Reproductive Medicine, which publishes the journal, said in a statement.
The researchers did not look at the link between fertility in general and HPV.
Dr. Steven Spandorfer and colleagues at the New York Hospital-Cornell Medical Center studied 106 patients scheduled to have IVF. They were all tested for HPV, HIV, chlamydia, and gonorrhea.
The women were all uninfected, except for 17 women who tested positive for HPV. These women were less than half as likely to conceive as women who either had never been infected, or whose bodies had successfully cleared the virus.
Genital HPV infection is very common, according to the U.S. Centers for Disease Control and Prevention.
About 20 million people in the United States alone are currently infected with HPV, the CDC says. At least 50 percent of sexually active men and women acquire genital HPV infection at some point in their lives -- more than 6.2 million Americans every year.
HPV can cause cervical cancer, which kills about 300,000 women worldwide each year, including about 4,000 in the United States.
Merck and Co. this year won a license for a vaccine called Gardasil, which prevents infection with the most dangerous strains of HPV. Vaccine experts recommend that most young girls receive it before they become sexually active.
Reuters Health
新闻来源：http://www.nlm.nih.gov/medlineplus/news/fullstory_38815.html
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