转基因小鼠在肿瘤学研究中的应用
FIG. Phorbol myristyl acetate stimulation of bioluminescence in transgenic mice.
For each mouse, the left ear was treated with PMA and the right ear with vehicle. A) Representative images obtained 2 hours after treatment are shown for two LTR-LUC mice (left panels) and two TAX-LUC mice (right panels) comparing bioluminescence following administration of D-luciferin (top panels) and Luminol (bottom panel). B) Histology showing edema and inflammatory infiltrate associated with topical application of PMA (48 hours; Bar = 1 mm). C) Aggressive lymphoma in TAX-LUC mice from intravenous administration of con A. D) Histology is H/E stained sections of bioluminescent tumors in the cervical lymph nodes and small intestine of a con A treated TAX-LUC mouse.
文章来源：
Rauch et al. Retrovirology 2009 6:116 doi:10.1186/1742-4690-6-116
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